Let’s look at his nose. Every human’s nose has some degree of asymmetry; his however appears to have increased over the past decade or so. See the picture below and look at his nostrils. On the left, they were slightly asymmetrical; on the right in a more recent photo, they look more off kilter.
Check out these other photos for differences. The first photo from above on the left is from the early 90s. The other photos are within the last two to three years.